Preformulation:
Physicochemical properties like physical form
Particle size
Shape
Density
Wetting
Dielectric constant
Solubility
Dissolution
Organoleptic additives
Hydrolysis
Oxidation-reduction
Recemization
Polymerization etc and their effect on formulation, stability and bioavailability study of prodrugs in solving problems related to stability bio availability in formulations
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